HLSC 1F90 Lecture Notes - Lecture 21: Lady Mary Wortley Montagu, Smallpox Vaccine, Opportunistic Infection

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Immunology is complex: full of details, exceptions to the rules and. , our knowledge is still evolving. Lets focus on the major concepts and the essence of how we naturally defend against infection: immunology is a team effort. Physiological mechanisms: humans and other animals use to defend their bodies from invasion by other organisms (but without harming yourself) Observing survivors of epidemic disease that were untouched (immune) when face to the same infection at a later time. Advantage of reproducing and evolving much more rapidly than their human hosts. Ie; ebola can reproduce every 20 minutes. Pit enormous populations of its species against and individual human: in response, the human body invests heavily in cells dedicated to defence, which collectively form the immune system. David philip vetter (1971-1984: aka bubble boy had sever immune de ciency, in the absence of a working immune system, even minor infections can take hold and prove fatal.

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