HLSC 2F95 Lecture Notes - Lecture 2: Hyaline Cartilage, Elastic Cartilage, Connective Tissue
Document Summary
Never exposed to environment outside of body. 3 basic components: specialized cells, extracellular protein fibers, fluid known as the ground substance. Cartilage: solid, rubbery matrix, hyaline, elastic, fibrous. Bone: solid, crystalline matric, connective tissue proper. Mesenchymal: respond to local injury or infection by dividing to produce daughter cells that differentiate into fibroblasts, macrophages, or other connective tissue cells. Fibroblasts: one of two most abundant fixed calls and are the only cells always present. Slender, star-shaped cells are responsible for the production of all connective tissue fibers. They secrets hyaluronan, which gives ground substance its viscous consistency. Fibrocytes: differentiate from fibroblasts, and are the second most abundant cell in ct. Following injury it is believed fibrocytes have the ability to dedifferentiate into fibroblasts, which may participate in the repair of the damages ct. Fixed macrophages: aka resident or resting macrophages, are large, amorboid cells that are scattered among the fibers.