HLSC 2P91 Lecture Notes - Lecture 4: Building Material, Riboflavin, Facilitated Diffusion

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4-13 year old consume 1. 8-3 times more than required. New indicator amino acid oxidation (iaao) technique. Protein requirements for 4-8 year olds may be underestimated. Large complex molecules found in the cells of all living things: critical components of all tissues, metabolism, communication. Synthesized in the body: dictated by genetic code. Essential: body cannot synthesize at all or in sufficient quantities to meet needs, has to come from diet, 9 aa. Nonessential: 11 aa, body can synthesize, transamination. Conditional essential: nonessential become essential, body fails to provide enough precursor, body cannot make this conversion, eg. phenyalanine -> tyrosine (pku) How are proteins made: link aa to form peptides (many possibilities, condensation reaction to form a peptide bond. Peptides: additional aa to dipeptide becomes a tripeptide, additional aa to a tripeptide become a polypeptide, most proteins are 30-300 aa long. Synthesis limiting: limiting aa (improper combination and quantity of essential aa- incomplete or low quality protein source)

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