HLSC 3P19 Lecture Notes - Lecture 1: Pharmacology, Experimental Physiology, Pharmacodynamics
15 Dec 2019
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Lecture 1: that interact with living systems through chemical processes, especially by binding to regulatory molecules and activating or inhibiting normal body processes. These substances may be chemicals administered to achieve: a beneficial therapeutic effect on some process within the patient, a toxic effect on regulatory processes in parasites (broad definition) infecting the patient. Medical pharmacology: science of substances used to prevent, diagnose and treat diseases. Toxicology: branch of pharmacology dealing with undesirable effects of chemicals on living systems, from individual cells to humans to complex ecosystems. Prehistoric people through experience: benefits and/or toxic effects of plants and animal materials, early records of remedies, some accepted as useful drugs today, some were worthless or harmful. But until the xv (15th) century, there was a lack of systematic experimentation and observation. In the late 18th and 19th centuries francois magendie and its student claude bernard began to develop the methods of: experimental physiology, pharmacology.
