HLSC 3P97 Lecture Notes - Lecture 1: Francesco Redi, Medical Microbiology, Antimicrobial Resistance

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Microbiology: the study of microorganisms and their interaction with other living organisms. Medical microbiology: the branch of clinical medicine devoted to the screening, diagnosis, prevention and treatment of diseases caused by infectious microorganisms. Factors influencing the decrease in infectious disease incidence in the 20th century. Surgeon general declared that microorganisms were defeated - did not account for new ones. Hiv wasn"t on our horizon until the late 1970s. Tb has been around for a long time, but it has evolved antibiotic resistance. Zoonotic infection: transmission from one species to another, ex. Strains such as o157:h7 (o represents sugar, h represents flagellum) Large inequality among causes of death in high/low income countries. The long and winding road linking microorganisms to disease. Experimented with meat in various containers to disprove spontaneous generation (belief that inanimate things could transform into living organisms) Concluded: flies only arise from maggot offspring of other flies cannot spontaneously generate from meat.

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