NEUR 2P37 Lecture Notes - Lecture 14: Panic Attack, Selective Serotonin Reuptake Inhibitor, Reuptake
24 Mar 2017
School
Department
Course
Professor
Document Summary
In depressed patients, the ventromedial prefrontal cortex increases autonomic and amygdala responses to the stimuli: the ventromedial and ventrolateral prefrontal cortex can decrease amygdala activity during emotion regulation but in depressed patients, the opposite effect occurs. Serotonin and mood: serotonin plays an important role in regulating mood: Subjects on a diet low in tryptophan, a precursor to serotonin, have a negative mood bias. Subjects also change connectivity in the ventral striatum and ventromedial prefrontal cortex to resemble patients w/ depression: selective serotonin reuptake inhibitors (ssris) alter mood: These are commonly used to treat depression. Even low doses can remove the negative mood bias. Use of ssris improves confidence and cooperative behaviours. ^ serotonin pathways in the brain: researchers manipulated the apparent pupil size of a person in a photograph, and they found that the subject appeared to be sadder when the pupils were larger.
