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Lecture 14

NEUR 2P37 Lecture Notes - Lecture 14: Panic Attack, Selective Serotonin Reuptake Inhibitor, ReuptakePremium

7 pages110 viewsWinter 2017

Department
Neuroscience
Course Code
NEUR 2P37
Professor
nickslothouber
Lecture
14

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NEUR2P37
Brain and Behaviour II
Friday, March 10th, 2017
Emotion III
Limbic Association Cortex: Modulation of Emotion
The Mechanisms of Emotional Reappraisal
The adjustment of emotional response based on context is known as reappraisal
There are changes in the activity of the lateral prefrontal cortex and anterior insula
when a subject reappraises the situation
There are also changes in connectivity between different regions during reappraisal
^Mechanisms of successful cognitive reappraisal
A set of areas in the prefrontal cortex are active during successful regulation of
emotional responses
The exert their effects by influencing the response of the nucleus accumbens and
amygdala to an emotional stimulus
When they succeed in altering the activity of these structures, cognitive reappraisal is
successful
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n healthy subjects, the ventrolateral prefrontal cortex activates the ventromedial
prefrontal cortex
his reduces autonomic and amygdala responses to the stimulus
In depressed patients, the ventromedial prefrontal cortex increases autonomic and
amygdala responses to the stimuli
The ventromedial and ventrolateral prefrontal cortex can decrease amygdala activity
during emotion regulation but in depressed patients, the opposite effect occurs
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