SCIE 1P51 Lecture Notes - Lecture 14: Adult Stem Cell, Blastocyst, Inner Cell Mass
Document Summary
Spare parts : end goal is to replace functionality when our own tissue stops working, other tissues have a minimal ability to regenerate function, harness what the body does naturally. Ancient practise: female mummy ~ 950-710 bce. Big toe carved out of wood & leather. Need the big toe to properly balance/walk. Using 3d printers to come up with customized parts for those who don"t have a lot of money/can"t afford it starting material if you want to start growing skin over it. Proteins what causes cells to grow (growth factors) Extracellular matrix (ecm: replicate a body environment outside of the lab. Scaffolds: natural biomaterials things we are taking out of nature, synthetic biomaterials things we can break down/control. Stem cells stem cells have a unique ability to renew themselves and give rise to the more specialized cell types. Allogeneic from another member of the same species.