PSYC 446 Lecture Notes - Lecture 10: Coeliac Disease, Diabetes Mellitus Type 1, Histocompatibility
18 Sep 2018
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Body"s reaction to infection, irritation or other injuries. Allows for different components of the immune response to be brought to the comprised site. Organ-specific or localized autoimmune diseases are those where only a single organ or tissue is directly damaged by the autoimmune process. The cause of autoimmune diseases is unknown, but it appears that there is an inherited predisposition to develop autoimmune disease in many cases. Three main sets of genes are suspected in many autoimmune diseases. A person"s sex also seems to have a major role in the development of autoimmunity. Most of the known autoimmune diseases tend to show a female preponderance. The symptoms and signs vary by specific autoimmune disease. Crohn"s disease: inflammation of the gastro-intestinal tract: genetic risk factor, environmental risk factor (more common in industrialized nations, affects 400,000 to 600,000 people in north america (loftus et al. , 2002)
