PSYC 455 Lecture Notes - Lecture 9: Neurofibrillary Tangle, Neuromuscular Junction, Nicotinic Acetylcholine Receptor

• School: Concordia University
• Department: Psychology
• Course: PSYC 455
• Professor: Wayne Brake

Document Summary

Lecture 9 alzhei(cid:373)e(cid:396)"s disease: alzhei(cid:373)e(cid:396)"s disease, dementia, as we age our brain cells die but the connections among them intensify, pre-senile dementia (alzhei(cid:373)e(cid:396)"s fo(cid:396) olde(cid:396) people(cid:895): You (cid:272)a(cid:374) o(cid:374)ly (cid:271)e diag(cid:374)osed (cid:449)ith alzhei(cid:373)e(cid:396)"s if you"(cid:396)e u(cid:374)de(cid:396) a (cid:272)e(cid:396)tai(cid:374) age: alzhei(cid:373)e(cid:396)"s, loss of memory at a certain age: Starts in the hippocampus (i. e. important area for declarative memory) and goes to the frontal cortex: cause: Amyloid plaques (i. e. stacks of protein that stick around the synapse, stopping it from working properly). Neurofibrillary tangles (i. e. tangles of protein inside the neuron leadi(cid:374)g to the (cid:374)eu(cid:396)o(cid:374)"s death(cid:895): Cholinergic neurons in the hippocampus are affected first. The (cid:374)u(cid:373)(cid:271)e(cid:396) of pla(cid:395)ues a(cid:374)d ta(cid:374)gles does(cid:374)"t (cid:396)elate to the severity of the disorder: Plaques and tangles are found in healthy old people"s (cid:271)(cid:396)ai(cid:374)s too (cid:894)i. e. so they a(cid:396)e(cid:374)"t the (cid:449)hole sto(cid:396)y(cid:895). If you ha(cid:448)e this ge(cid:374)e, you ha(cid:448)e (cid:1009)(cid:1004)% (cid:272)ha(cid:374)(cid:272)e of getti(cid:374)g alzhei(cid:373)e(cid:396)"s: symptoms: There is not cure, only treatments available: