PSYCO403 Lecture Notes - Lecture 6: Neurofibrillary Tangle, Amyloid, Alois Alzheimer
22 Mar 2020
School
Department
Course
Professor
Document Summary
Status and performance in regard to na, mci and ad. Looking at more distal conditions not necessarily a precursor but it is a factor. Ex. distal condition for ad could be hypertension, depression, etc. Lifetime influences demanding processes early symptoms ndd. Need to understand the overlap and the differences between ndd. Ich hab mich verloren i have lost myself . Dementia umbrella term of loss of memory, reason, language and judgment. Don"t know if plaques or tangles form first. Initially in the cortex, then hippocampus, then the rest of the brain. Tau supports neurons and provides them with nutrients. Ad causes changes in tau that result in tangles, collapsing microtubules and neurons transport system. Progression of lesions follows symptoms of the disease. Mutation in any of these leads to familial. Multifactorial (combination of a bunch of risk factors) Why some mci patients convert and some don"t. Some of the changes that unfold during ad.
