BIOL 2020 Lecture Notes - Hydrolysis, Mapk1, Caenorhabditis
Document Summary
Cell signaling and signal transduction: communication between cells: 605-630, 642-646, 653-657. Target cell is usually distant. messenger molecule outside of cell: ligand. First messenger is also called a ligand; sticks to receptor outside of the cell when a ligand binds to a receptor (they are specific), the interaction causes a signal across the cytoplasmic domain that can cause 2 different pathways: Two types of cell signaling: signal transmitted by second messenger. Receptor has an effector (an enzyme), which activates a second messenger. Second messengers are small molecules that typically activate (or inactivate) specific proteins. Based on phosphorylation of the receptor, and then because its phosphorylated, proteins get recruited to the cell surface. What cell signaling can activate: transcription survival protein synthesis movement cell death metabolic change signal transduction: process of information being carried by extracellular messenger molecules that translate a change inside a cell.