PHAC 4001 Lecture Notes - Lecture 20: Insulin Receptor, Hyperlipidemia, Polydipsia

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Phac 4001 lecture 20 march 5, 2021 therapeutic approaches to diabetes i. Pathobiology of type 2 diabetes: glucose homeostasis and pancreatic hormones, other anti-hyperglycemic agents (in the context of type ii diabetes) Insulin replacement therapy (in the context of type i diabetes) Glucose is a primary energy source for all tissues. Glucose is particularly important for organs like the brain, which consumes about. 60% of the glucose that is in the body. Glucose can be utilized via the glycolysis and subsequently enter the tca cycle to generate atp. Atp can be used by all cell types to drive all sort of critical cellular processes (ie. metabolic enzymes, dna replication and gene expression). Because glucose is such an important primary cellular energy source, it is important an adequate supply of glucose in present in the bloodstream in order to sustain the various cells of the body.

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