BIOL 112 Lecture Notes - Lecture 18: Alkaptonuria, Epistasis, Uracil

• School: McGill University
• Department: Biology
• Course: BIOL 112
• Professor: Frieder Schoeck

Document Summary

The sequence of nucleotides is not constrained by structure , dna can accommodate any sequence and any sequence can encode info. Interaction between albino and agouti locus (a/a) and albino locus (c/c) If recessive at c locus, mouse will be albino regardless of genotype at a/a locus (c is epistatic on a) Alkaptonuria : caused by recessive hereditary trait, results from absence of a specific enzyme, so gene. Enzyme gene specifying each enzyme, thus one gene specifies one protein. Rna transfers the genetic information from the nucleus to the cytoplasm where the proteins are made. Rna similar to dna, but replaces at with au (uracil) and has an extra oxygen on the 2" carbon. Synthesized by rna polymerase through addition of ntps (nucleotide triphosphates) in transcription. Template rna used to synthesize protein in translation using trna"s , each charged with one amino acid.