BIOL 115 Lecture Notes - Lecture 5: Chromosomal Translocation, Reading Frame, Chromosome
25 Jun 2016
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Frame shift mutation can result from an insertion or deletion and changes the reading frame from that point onwards. Inversion when a piece of the dna flips around, re-entering the chromosome in the reverse orientation abcdefg ab/edc/fg: translocation results when a piece of dna jumps from one chromosome to another. If somatic, then the change could kill the cell, make it sick or cancerous. Although the mutation will be inherited by the mitotic progeny, the change will not be transmitted to the progeny as somatic cells do not make gametes. If in the germ line mutation, which does produce gametes, an egg or sperm may end up with the mutated gene and transmit it to progeny. Thus, the mutation (if not too deleterious) will become part of a repertoire of alleles present in that population of organisms. It is on these germ line mutations that natural selection acts to produce new species.
