BIOL 200 Lecture Notes - Lecture 13: Alternative Splicing, Dscam, Rna Editing
Document Summary
Biol 200 - lecture 13, rrna and trna. Alternative splicing is one gene that produces different proteins depending on the cell type and when the cell is acting. Contains 4 different exons that can be alternatively spliced. Many different isoforms can be produced from each exon. Isoform = different mrnas expressed by the same gene. Exon light blue contributes for 12 isoform, exon green for 48 isoforms, exon dark blue for 33 isoforms, an exon yellow for 2 isoforms. The combination of these 4 exons are plenty. You can have isoform 4 from light blue, with isoform 36 from green, with 21 from dark blue and 1 from yellow. This is only one combination, but you can make a lot of different combinations from this gene. Many isoforms of the slo proteins are made by alternative splicing. Each isoform will respond to a specific air vibration which will enable you hear. This alternative splicing is very important for us.