BIOL 200 Lecture 40: 40

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lilacturtle126

14 Jun 2016

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Pre-rrna transcription units are arranged in repetitive clusters (cid:120) since rrna accounts for approx. 80% of the total rna in the cell, it has to be transcribed extensively to be able to (cid:120) satisfy the continuous demand. If (cid:455)ou take a(cid:374) (cid:396)dna (cid:272)luste(cid:396) a(cid:374)d put it so(cid:373)e(cid:449)he(cid:396)e else, it"s e(cid:374)ough to (cid:271)uild up a(cid:374) e(cid:374)ti(cid:396)e o(cid:396)ga(cid:374)elle (cid:449)ithi(cid:374) the (cid:374)u(cid:272)leus. The trnamet is needed to start synthesis of a polypeptide chain (cid:120) (cid:120) Initiator trnamet is exclusively used for intiation of a polypeptide. I(cid:374) (cid:271)a(cid:272)te(cid:396)ial, it"s (cid:373)odified so it"s different from the trna met used during chain elongation: the(cid:396)e"s a fo(cid:396)(cid:373)al g(cid:396)oup attached to it which distinguishes it from other trna mets. It brings along eif4a, eif4b, and eif4g: eif4g binds eif3 and pabp1. It interacts with the component of the pre- initiation complex to bring it down to a substrate (cid:120)

Related Questions

1- Elongation Factor Tu and GTP allow tRNAs to enter the A site and form the appropriate codon/anticodon binding. Elongation Factor _______ regenenerates Tu.

2- When a stop codon arrives in the A site, _________ or 2 bind to it and cause the release of the polypeptide.

3- There are 61 sense codons and 3 stop codons, but only 20 amino acids - thus the code is _______.

4- The idea that genes encodes proteins was first put forth by __________ in 1908 but not widely accepted until the 1940âs following the work of Beadle and Tatum.

5- In tRNA ________ (with an amino acid), a single ATP is required.

22. There are 20 amino acids and 64 possible codons. Which of the following is closer to the actual number of different tRNA molecules in a cell?

A. 4

B. 16

C. 20

D. 61

E. 64

23. There are 20 amino acids and 64 possible codons. How many different eukaryotic aminoacyltRNA synthetases are there? A. 1

B. 16

C. 20

D. 61

E. 64

24. Which way are the amino acid and tRNA attached in a charged tRNA?

A. Amino acid-5'tRNA3'-AMP B

. Amino acid-AMP-3'tRNA

C. AMP-amino acid-3'tRNA

D. Amino acid-3'tRNA5'-AMP

E. Amino acid-AMP-5'tRNA

25. The anticodon that recognizes the initiation codon in translation is

A. 5' AUG 3'

B. 3' AUG 5'

C. 5' ACU 3'

D. 5' UAC 3'

E. 3' UAC 5'

26. The first amino acid incorporated into a growing polypeptide

A. In bacteria is methionine and it is also methionine in eukaryotes

B. In bacteria is tryptophan, while it is methionine in eukaryotes

C. In bacteria is N-formyl methionine, while it is methionine in eukaryotes

D. In bacteria is N-formyl methionine and it is also N-formyl methionine in eukaryotes

E. In bacteria is methionine, while it is N-formyl methionine in eukaryotes

27. In E. coli the IF3 forces tRNAf Met to bind with

A. The A site of the ribosome

B. The P site of the ribosome

C. The E site of the ribosome

D. IF1

E. IF2

31. T or F. In pre-mRNA splicing, the 5â splice site, 3â splice site, and the cleavage site in the
intron sequence each have a consensus nucleotide sequence.
32. T or F. The addition of an amino acid to a tRNA molecule is an example of a molecular
switch.
33. T or F. The binding of a ligand to its specific plasma membrane receptor is an example
of a molecular switch.
34. T or F. Energy obtained from ATP hydrolysis is used to attach each amino acid to its
tRNA molecule in a high energy bond that is used later in the ribosome to join an amino
acid into the polypeptide chain.
35. T or F. Every new protein, as it emerges from RNA polymerase in the nucleus, is
comprised of amino acids that have been joined together in a linear chain.
36. T or F. The ribosome has a total of 3 RNA binding sites, including the A, P, and E sites.

BIOL 200 Lecture 40: 40

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