BIOL 201 Lecture 12: Lecture 12
Document Summary
You are at a concentration where the amount of atp actin that"s been added to the plus end is equal to the amount of adp actin that is coming off the minus end. Loss of actin from the minus end will cause the end to shrink towards the blue. Actin regulators allow cells to build diverse and dynamic actin networks. 2 actin binding domains are present in the same polypeptide. Actin binding domains are individual polypeptide, which then dimerize to form a domain that can hold single protein that can hold onto two actin filaments. The bundles are tighter in the case of fibrin than alpha actin. At the leading edge, we find the flexible cross linker. The leading edge of a moving cell is a branched actin network. Actin polymerizing at the top--> must be depolymerizing at the back. A pathogenic bacterium hijacks the actin machinery of human cells.
