ANAT 261 Lecture Notes - Cuticle

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Lab 2 – Skin Appendages
Sweat Gland
simple, coiled, tubular gland
contained within an BM
merocrine secretion
ocells NOT histologically modified when they secrete sweat (retain
normal shape)
two portions of the gland:
osecretory portion
exclusively found within the hypodermis
formed by single layer of pyramidal cells
pyramidal cells stain pink and pale
surrounded by myoepithelial cells that can contract (to push
sweat up duct)
myoepithelial cells stain only slightly darker
oexcretory duct
found in dermis and epidermis
~2 layers of cuboidal epithelium
no myoepithelium
more acidophilic and darker than secretory portion
small lumens
Hair
layers of hair follicle from outside in
oglassy membrane
modified BM that is very thick and visible
extends from epidermal BM
oexternal root sheath (ERS)
thickest layer
does not stain well; appears pale
ointernal root sheath (IRS)…3 distinct layers:
Henley’s layer
single layer of squamous cells without visible nuclei
does not stain well
Huxley’s layer
several layers of squamous cells that contain acidophilic
TRICOHYALINE granules
(don’t confuse with KERATOHYALINE granules!)
cuticle of the IRS
one layer of pale cells
ocuticle of hair shaft/cortex
very thin, basophilic layer
ocortex
bulk of hair; keratinized cells
omedulla *not seen on slides (will not need to be identified)
Mnemonic for hair layers:
George
Entered
Henry’s
House
Carrying
Cookies
Glassy
membrane
ERS
Henley’s
Huxley’s
Cuticle of IRS
Cuticle of hair
shaft
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