CHEM 232 Lecture Notes - Lecture 4: Acetic Anhydride, Magnetic Stirrer, Aspirin
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Scenario: synthesise an import chemical compound, purify the compound by recrystallization, analyze the product by melting point determination and fecl3 color test for phenols, use the stoichiometry of the reaction to determine the percent yield of the reaction. For this lab, you will put yourselves in the shoes of felix ho man, a chemist at bayer pharmaceutical. You will recreate his synthe- sis of aspirin from salicylic acid and acetic anhydride that he rst completed in 1897. Aspirin as one of the most import drugs of the 20th century, a drug still available in pharmacies worldwide today. In this experiment you will prepare a sample of aspirin, recrystallize the raw product, and determine the percentage yield of the aspirin based on the limiting reactant. Aspirin is used medically to reduce fever and pain. It is a deriva- tive of salicylic acid (which is also an antipyretic) but is less acidic, and therefore less irritating when taken by mouth.
