EDKP 395 Lecture Notes - Lecture 18: Lactic Acid, Hypoventilation, Biceps

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Regulation of arterial blood [h+] during progressive exercise. In humans, arterial blood [h+] (left) is regulated by ventilatory elimination of co2 from mixed-venous blood (right) during progressive exercise, particularly at intensities above the lactic acidosis threshold (lat) aka the ventilatory/anaerobic threshold. During exercise in health, vt expands by increasing eilv into the available irv and by decreasing eelv into the available erv. Fro(cid:373) a ph(cid:455)siologi(cid:272)al perspe(cid:272)ti(cid:448)e, (cid:449)h(cid:455) does it (cid:373)ake (cid:862)se(cid:374)se(cid:863) that tidal (cid:448)olu(cid:373)e (cid:894)vt) expands to. Feedforward & feedback control of breathing during exercise. From the central respiratory controller, we have information that goes to the airways, to the respiratory muscles and to the respiratory pump muscles in particular, through the phrenic and vagus nerve, also have innervation of locomotor muscles. Can have parallel activation of both the breathing and locomotion. Central chemoreceptors are primarily sensitive to the acidity of the cerebral spinal fluid ([h+]) Carotid (cid:272)he(cid:373)ore(cid:272)eptors are se(cid:374)siti(cid:448)e to (cid:894)look at graph)

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