LSCI 211 Lecture Notes - Lecture 16: Nucleobase, Phosphodiester Bond, Pentose
28 Aug 2016
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Document Summary
Linked to sugar by covalent n-glycosidic bonds through a condensation reaction. Griffit"s experiment provided evidence for nucleic acids as a storage of genetic material. Right handed helix with two complementary anti-parallel strands. Bases are stacked inside and held together by h-bonds and van der wall interactions. 2nm wide, with a 0. 34nm separation between bases along the helical axis. 10. 4 nucleotides per helix turn (pitch of 3. 6nm) The flow of information from genes to proteins. Dna is replicated, and transcribed to rna then translated to protein. Semi-conservative- each new strand of dna has a parent and daughter strand.
