NSCI 300 Lecture Notes - Lecture 12: Carl W. Ernst, Intellectual Disability, Centre For Addiction And Mental Health

• School: McGill University
• Department: Neuroscience
• Course: NSCI 300
• Professor: Eric Racine

Document Summary

Would place everyone in almshouses/poorhouses (us), jails, penitentiaries. Living conditions were terrible: curables vs. incurables, everybody was sending everybody to the asylums, but institutions wanted to separate curables from incurables (who are the ones who should be sent to the asylums) Linked an std with a new mental health category, feeble-mindedness . Lots of genomic variations, most are benign/have no effect. Speaker : carl ernst, phd: some terminology, cloning = taking an unfertilized egg, injecting dna from somewhere else, and having that egg develop. Not viable as a technology : for dolly the sheep, 227 attempts, only 29 viable embryos implanted, only 1 birth. [now, rather in the should we than the can we ] Speaker : carl ernst, phd: could modify cas9, to selectively turn on a gene (eg to push it over a particular developmental hump), or to trigger a selective histone methylation (= messing with the epigenetic patterning)