PHAR 562 Lecture Notes - Lecture 13: Asperger Syndrome, Hans Asperger, Frontal Lobe

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Severity determined by adaptive functioning deficits instead of iq. Child will not be responding well to parents, lack of eye contact, difficulty with communication. Adaptive functioning divided into conceptual, social and practical domains. Excessive levels of activity: fidgeting, squirming, running around at inappropriate times, incessant talking. Distractibility and difficulty concentrating: making careless mistakes, inability to follow instructions, forgetfulness. Congress created national adhd awareness day: first observed sept 7, 2004. 3 subcategories in dsm-v-tr: predominantly inattentive type, predominantly hyperactive-impulsive type, combined type. Ddx: adhd or conduct disorder, adhd, more off-task behaviour, cognitive and achievement deficits, conduct disorder, more aggressive, act out in most settings, antisocial parents, family hostility. How can you determine in a live patient, whether or not appropriate synaptic pruning has occurred: mri might work, otherwise, you need to wait post-mortem. If you have more connections denser mass, enlargement of certain brain regions.

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