PHGY 209 Lecture Notes - Lecture 4: Folic Acid, Viscosity, Ileum
11 Oct 2017
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Has its effect in the committed myeloid stem cells, not in the pluripotential stem cells. It will accelerate their maturation of the committed stem cells. Testosterone increases the release of epo and increases the sensitivity of committed stem cells to epo. Reason why males have more rbcs than females. Life span of rbcs of around 120 days. Fun fact, each rbc travels around 300 miles. Nothing can prolong the life span of rbcs. Old rbcs are recognized and are removed from the circulatory system by phagocytic cells (cells that like to eat things) called macrophages, which will be covered during the immunology lectures. Macrophages put out pseudopodia that engulfs the old rbc and will break the membrane. The lysosomes will break down all the hb and release its content into the blood stream. Heme pigments will be broken down into biliverdin (green color) which will be broken in the plasma into bilirubin (yellow color) which gives the plasma its color.
