PHGY 210 Lecture Notes - Lecture 1: Posterior Pituitary, Neurohormone, Pituitary Stalk

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Involves hormone secretion into the blood by an endocrine gland. The hormone is transported by the blood to a distant target site. Release of a hormone by a neuronal cell cells from the hypothalamus and the posterior pituitary. Paracrine signalling between one cell and an adjacent cell. Autocrine signalling between a cell and itself. Via blood vessels of the pituitary stalk. Hypothalamic-hypophyseal portal system from the hypothalamus to the adenohypophysis (anterior pituitary) Hypothalamic neurohormones either activate or inhibit activity of one of the six types of hormone- producing cells in the anterior pituitary. Called either releasing hormones (releasing factors) or inhibiting hormones (inhibiting factors) Glycoproteins are proteins that are glycosylated after the peptide has been synthesized. Glycoproteins and polypeptides are encoded by a gene, steroids and amines are not. Estradiol is essential for normal male physiology. Estradiol is produced in measurable quantities during the female reproductive cycle while estrogen is produced locally in males.

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