PHGY 311 Lecture Notes - Lecture 7: Small Cell, Resting Potential
7 Oct 2018
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Local signaling: passive electrical properties of the neuron. Epsps are subthreshold so a neuron has to summate many epsps together to reach threshold. Time frame that 2 epsps have to land on the neuron in order to be summed. These ion channels govern the resting potential. They allow charge to flow through them. Charge flow to the membrane to change the charge on the membrane (q) The current that flows when ion channels open can only flow in a complete circuit: across the membrane and back to the source. Through the resting ion channels (cid:894)si(cid:374)(cid:272)e the (cid:373)e(cid:373)(cid:271)ra(cid:374)e (cid:271)ilayer does(cid:374)"t allo(cid:449) io(cid:374)s to flow) which resist the flow of current. When current goes through the circuit resistance. Conductance is the reciprocal of the resistance: g = 1/r where r is the resistance of the channels to synaptic current. Range of conductance: 0. 5 to 100 ps for single channel conductance. Sum of all channels open at rest.
