PHGY 210 Lecture Notes - Potassium Channel, Beta-Adrenergic Agonist, Sinoatrial Node
14 May 2012
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Palpation means using the sense of touch to make the measurement. Korotkoff sounds: hear sounds systolic pressure, when the sounds go away diastolic pressure. Looking at the pulsations of the pressure in the cuff. Need bp to be different depending on what you"re doing, need regulation if you ever get hurt, for example. Map (mean arterial pressure) = ~100 mmhg memorize. Many of the organs autoregulate: brain, heart, kidneys. The heart is the first organ to be fed by the arterial system. Two methods of autoregulation: metabolic component, myogenic component. Neural control of the heart of vessel see slides for sympathetic and parasympathetic control of breathing. Receptor on sa node is a potassium channel. Ach molecules bind to k+ channel, k+ ions leave the cell, hyperpolarization of the cell results. Slope at pacemaker potential is reduced (see change in rate of sa node slide)
