BIOCHEM 3H03 Lecture Notes - Lecture 11: Autonomic Nervous System, Pituitary Adenoma, Sella Turcica

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Compensation by nuclei of the hypothalamus via 2 main outputs: neural signals to the autonomic nervous system. Controlling heart rate, vasoconstriction, digestion, sweating etc: endocrine signals to/through the pituitary. Small gland ( ~500 mg) located at the base of the skull in a bone cavity known as the sella turcica (turkish saddle) Often referred to as the master gland because the battery of hormones produced by the pituitary influence virtually every physiological process in the body. The pituitary is comprised of the: anterior pituitary or adenohypophysis is a classical gland consisting largely of cells that secrete protein hormones, posterior pituitary or neurohypophysis is not a true organ but rather an extension of the hypothalamus. Consists largely of hypothalamic neurons which extend downward as a large bundle behind the anterior pituitary. Pituitary is the master but the hypothalamus is power behind the throne. Unique vascular system between hypothalamus and pituitary link nervous system to endocrine system.

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