BIOCHEM 2EE3 Lecture 8: Biochem module 8 – citric acid cycle

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19 Feb 2020

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Citric acid cycle: location: the citric acid cycle takes place in the matrix, or fluid, of the mitochondrion. This is where mitochondrial dna is found and where fatty acid breakdown takes place: summary: citric acid cycle involves eight chemical reactions that use acetyl coa and oxaloacetate to produce carbon dioxide, nadh, atp, and fadh2. The nadh and fadh2 are electron carriers that can be used in the electron transport chain to make more atp for a cell: steps: let"s take a look at the major steps of the citric acid cycle. So, two carbon dioxides are formed during the conversion of the 6-carbon molecule back to the 4-carbon molecule: so, where does the 2-carbon molecule come from to begin the citric acid cycle, 2 carbon molecule = acetyl coa. This molecule, acetyl coa, is made from pyruvate. Pyruvate is a product of glycolysis, the other major atp producing cycle in the cell.

Related Questions

Which of the following is not a net product of the citric acid cycle for each molecule of pyruvate generated in glycolysis?

Select one:

a. 1 ATP (GTP)

b. 1 acetyl coA

c. 3 NADH

d. 1 FADH2

Question 2

Which of the following is NOT an end product for an acetyl group that enters the citric acid cycle?

Select one:

a. ATP

b. NADH

c. FADH2

d. oxaloacetate

Question 3

Once they have been processed through the citric acid cycle, the acetyl-CoA molecules from a single glucose molecule produce:

Select one:

a. 2 ATP, 6 NADH, 4 CO₂.

b. 6 NADH, 6 GTP.

c. 6 FADH₂, 2 ATP, 6 CO₂.

d. 6 GTP, 6 FADH₂.

e. 4 CO₂, 6 FADH₂, 2 ATP.

Question 4

The products of the citric acid cycle breaking down 2 acetyl-CoA include 2 ATP (converted from GTP), 6 NADH and 2 FADH2.

Select one:

True

False

7. In metabolism, food gets oxidized and the coenzymes NAD⁺ and FAD are reduced.

	True
	False

8. Which of the following does not undergo oxidation or reduction during metabolism?

	A. lipids
	B. Coenzyme A
	C. carbohydrates
	D. FAD

9. Which of the following is not a coenzyme?

	A. NAD⁺
	B. Coenzyme A
	C. ATP
	D. FAD

10. Which of the following is false regarding FAD?

	A. FAD is an oxidizing agent.
	B. FAD is the oxidized form.
	C. FAD is a coenzyme
	D. FADH₂ is an oxidizing agent.

11. How many carbon atoms are present in an acetyl group?

	A. 1
	B. 2
	C. 3
	D. 4

12. The purpose of coenzyme A is to deliver acetyl groups to the citric acid cycle.

	True
	False

13. What reacts with NADH and FADH₂ to form NAD⁺ and FAD?

	A. carbon dioxide
	B. water
	C. ATP
	D. oxygen (and H⁺)

14. Which metabolic process oxidizes NADH and FADH₂

	A. electron transport chain
	B. oxidative phosphorylation
	C. citric acid cycle
	D. hydrolysis

15. Which metabolic process converts ADP to ATP?

	A. electron transport chain
	B. oxidative phosphorylation
	C. citric acid cycle
	D. hydrolysis

___ 25- The Krebs cycle begins with the union of acetyl CoA with oxaloacetate forming citrate, allowing oxidative decarboxylation reactions to occur, and ends with the conversion of malate to oxaloacetate. Using this information and your knowledge of the Krebs cycle, how many net carbons does the citric acid cycle gain?
A) 0 carbons
B) 1 carbon
C) 2 carbons
D) 4 carbons
___ 26- Directly from the Krebs cycle we can obtain:
A) ATP
B) GTP and NADPH
C) ATP and NADPH
D) ATP, GTP, and NADPH
___ 27- Which of the following is not an intermediary of the Krebs cycle?
A) oxaloacetate
B) citrate
C) succinyl CoA
D) acetyl CoA
___ 28- How many di nucleotides are reduced by four turns of the Krebs cycle?
A) 1 FADH2 and 4 NADH
B) 2 FADH2 and 8 NADH
C) 4 FADH2 and 12 NADH
D) 1 FAD and 4 NAD +

BIOCHEM 2EE3 Lecture 8: Biochem module 8 – citric acid cycle

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