BIOLOGY 3P03 Lecture Notes - Lecture 20: Glycerol, Arginine, Sorbitol
28 Dec 2017
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Cell swelling occurs during : hypoxia/ischemia, increases in extracellular potassium concentrations, hyponatremia (decrease in sodium concentrations) in situations when hormonal and renal function is impaired, hypothermia, which inhibits the na+/k+-atpase. Cell shrinkage occurs during : hypernatremia following excessive na+ intake or eater loss (dehydration, reduced extracellular k+ concentrations. Swelling occurs when na+/k+-atpase is inhibited: occurs via hypothermia or ouabain toxin. #1: osmotic equilibrium is maintained by an equal number of positive and negative. Monday, november 20, 2017 ions moving in and out of cell. Levels of intracellular anions and potassium are high. Swelling cell after na+-k+ pump is inhibited : recall: sodium normally transported out and potassium transported in, addition of ouabain causes continued passive leakage that disrupts the osmotic equilibrium- water ows into cell, causing it to swell. Passive entry of three sodium ions exceeds the net positive e ux of two potassium ions: levels of extracellular sodium and chloride are high.
