BIOLOGY 1A03 Lecture Notes - Lecture 2: Fluid Mosaic Model, Lipid Bilayer, Fluorescent Tag

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BIOLOGY 1A03
Theme 1 Module 1 & 2 Review
Module 1: The composition & structure of membranes
Different Lipids Can be Found in Cells
Typically, there are 16 or 18 carbons in a single chain.
The bonds connecting the carbons may be single bonds (saturated) or double bonds
(unsaturated). (the kinked tale)
These properties change the shape, size, and behaviour of the phospholipids and ultimately the
membranes.
Many Factors affect the Fluidity of Cell Membranes
1. Unsaturated (more fluid) or saturated (more solid) fatty acids
2. Number of carbons in the fatty acid tails
3. Temperature (higher temperatures favour fluidity)
4. The presence or absence of cholesterol (make areas more hydrophobic)
Visualizing lateral mobility in the cell membrane
If fluid, the fluorescent tag labelled on a protein would make up for each other when portion
bleached
Cell Membranes are Selectively Permeable
• The aility of ell membranes to control the traffic of substances into and out of the cell and its
organelles makes them selectively permeable.
Hydrophobic molecules (O2, CO2, N2) able to go through the membrane
Small, non-polar molecules (urea, glycerol) able to go through the membrane
Large, charged polar molecules (glucose, sucrose (large) & ions) unable to go through the
membrane
The Fluid Mosaic Model
• The Fluid Mosaic model: membranes consist of proteins and carbohydrates embedded in a fluid
phospholipid bilayer.
Proteins are also amphipathic
Movement Across the Cell Membrane
Passive diffusion: from areas of high to low concentration (along a gradient).
Passive transport: or facilitated diffusion: from areas of high to low concentration (along a gradient).
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BIOLOGY 1A03 Full Course Notes
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BIOLOGY 1A03 Full Course Notes
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Document Summary

Module 1: the composition & structure of membranes. If fluid, the fluorescent tag labelled on a protein would make up for each other when portion bleached. Large, charged polar molecules (glucose, sucrose (large) & ions) unable to go through the membrane. The fluid mosaic model: the fluid mosaic model: membranes consist of proteins and carbohydrates embedded in a fluid phospholipid bilayer. Passive transport-an analogy: passive transport: or facilitated diffusion: from areas of high to low concentration (along a gradient). Active transport-an analogy: active transport: molecules move against the concentration gradient (fuelled by energy from the hydrolysis of atp). Photosynthesis: a process used in plant cells and other organisms to convert light energy into chemical energy. Chemical energy is stored in the bonds of carbohydrate molecules: using sunlight to produce carbohydrates. Co2 + 2 h2o + light energy --> c6h12o6 + h2o + o2. A proton gradient drives the synthesis of atp: electron transport chain.

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