BIOLOGY 1A03 Lecture Notes - Lecture 8: Histone Acetyltransferase, Tata Box, Methyl Group

• School: McMaster University
• Department: Biology
• Course: BIOLOGY 1A03
• Professor: Jurek Kolasa

Document Summary

Biology 1a03 theme 3 module 3 and 4. 200 disinct cell types in adult human bodies. Variaion in specialized cell types are largely. Early embryonic cell divisions dependent on the difereniaion that occurred from common stem cells during the early developmental cascade. Transcripion factors oten work with other proteins that can result in various changes in gene expression during successive cell division as cells mature throughout development. Controlling which genes are acive along the chromosome leads to the vast array of cell types. Chromain must unravel in order for transcripion to occur. Dna ightly wound around a complex of histone proteins, forming the nucleosome structure. Nucleosome contains an octamer of 8 histone proteins around which approximately 150. Begins when an acivator protein or transcripion factor is able to bind to an accessible enhancer site, leading to the further recruitment of other proteins that can lead to further chromain remodeling.