BIOLOGY 1M03 Lecture Notes - Lecture 10: Twin, Pharmacogenetics, Melanocyte
31 Jan 2018
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Document Summary
Theme 3, modules 3 & 4 responding to the environment. There are multiple levels of gene expression regulation. What is it: a multitude of chemical compounds that can tell the genome what to do. They change the way cells use the dna"s instructions: the marks are sometimes passed on from cell to cell as cells divide. They also can be passed down from one generation to the next. What does it do: the differences among cells are determined by how and when different sets of genes are turned on or off in various kinds of cells, the epigenome controls many of these changes to the genome. Epigenetic processes are essential for normal development, cell differentiation, and are increasingly being recognized as being involved in human diseases. Epigenetic mechanisms: epigenetics study of epigenetic modifications across entire genome: modifications of histone tails, dna methylation, chromatin remodeling, packaging of dna around nucleosomes.
