BIOLOGY 2A03 Lecture Notes - Lecture 4: Active Transport, Electrochemical Gradient, Passive Transport

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Glucose uptake against its concentration gradient by co- transport with na+ relies on the na+ gradient established by the sodium potassium atpase. Osmosis: osmosis is the passive diffusion of water across membranes. Membranes are permeable to eater, due to its small size, even though it is a polar molecule: water diffusion occurs down its concentration gradient. 1m of glucose in solution = 1osmole but 1m of nacl = 2 osmoles since it ionizes in solution to na+ and cl- This cre4ates the osmotic driving force for water diffusion into the cell hypotonic solution. Epithelial water transport: movement of water across an epithelial cell layer occurs by osmosis, and depends upon the active transport pf solutes to create an osmotic gradient. Epithelial transport: transcellular transport transport through epithelial cells, transcellular transport of water requires dedicated channels called aquaporins, paracellular transport transport between epithelial cells (only possible for those substances that can pass through tight junctions)

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