BIOLOGY 2B03 Lecture Notes - Lecture 8: Biological Membrane, Cytosol, Ribbon Diagram

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sangriachimpanzee60

28 Mar 2018

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Rough endoplasmic reticulum (rer: bound by a single membrane - continuous with the outer membrane of the nucleus, does not have it own genome, all proteins required for er function are coded in the nuclear genome. Site of some protein synthesis and of protein modification: not the final destination for all proteins, many proteins will be transported to other locations of the cell. Include the golgi apparatus, the lysosome, the cell membrane and even secreted out of the cell. Tem of endoplasmic reticulum: punctate black dots on rough er represent membrane associated ribosomes that are synthesizing secretory proteins (red, these proteins travel through the golgi apparatus and in vesicles to reach the outside of the cell. Some ribosomes are not associated with the er and can be seen free and in the cytosol common pool: they are simply cycling on and off the er membrane. Specific to er: this is gtp hydrolysis, either the lumen or the membrane.

Related Questions

1A. Which of the following statements about the endomembrane system is/are correct? (select all that apply)

A.	Secreted proteins are inserted into the ER as they are being made by ribosomes.
B.	the nucleus is surrounded by two phospholipid bilayers.
C.	"Free" ribosomes attach to the endoplasmic reticulum.
D.	Secreted proteins are moved from the ER to the Golgi by ribosomes

1B. Place these components of the endomembrane system into the correct order in respect to when they first function in the production of a secreted protein.

	Endoplasmic Recticulum (ER)
	Riibosome
	Nucleus
	Transport Vesicle
	Cell Membrane
	Golgi Apparatus

lilacgnat89

Which of the following statements about secreted proteins is/are correct? Choose all that apply. Which of the following statements about secreted proteins is/are correct? Choose all that apply.

Secreted proteins travel directly from the rough endoplasmic reticulum into the trans face of the Golgi apparatus.

Secreted proteins are likely to have received N-linked glycosylation in the rough ER.

Secreted proteins are the only proteins that receive sugar modifications in the Golgi.

Secreted proteins that are constitutively expressed are exported as they are prepared, as opposed to being released as a response to a signal.

Secreted proteins are synthesized on membrane-bound ribosomes, not free cytosolic ribosomes.

sangriacat694

Complete the following sentences to examine various components of the endomembrane system.

Information within the ____________ is transcribed into mRNA and transported outside the nuclear envelope.

Proteins, which are synthesized by ____________ , are then released into the ____________ , where they are further folded and modified.

The ____________ does not have attached ____________ and produces lipids, such as steroids.

Once proteins are folded and modified, transport vehicles called ____________ pinch off and surround them with membranes to be transported elsewhere.

The vesicles are moved to the ____________ where they are sorted and packaged.

Transport vehicles called ____________ carry the macromolecules to the ____________ where they fuse and release their contents to the outside environment.

ribosomes

Golgi apparatus

smooth endoplasmic reticulum

vesicles

plasma membrane

rough endoplasmic reticulum

nucleus

secretory vesicles

BIOLOGY 2B03 Lecture Notes - Lecture 8: Biological Membrane, Cytosol, Ribbon Diagram

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