BIOLOGY 2B03 Lecture Notes - Lecture 1: Molecular Motor, Tyrosine, Protein Structure
30 Aug 2016
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Document Summary
Bio2b03 - module 1: amino acids & chemical reaction. Principles of the primary structure of a polypeptide. Protein: a string of amino acids; a polypeptide chain; a polymer of other small molecules. Structural components of the cell: tubules, actins & cytoskeleton elements. Sensors for environmental change & mechanisms for relaying such information. Cell-to-cell signalling: signals, receptors & components of transduction pathways. Shape & structure of protein specifies its function (i. e. the substrate binding domain & activity domain) Glutamine synthetase: large, donut-shaped structure; active domain in the middle. Note: final functional form of insulin is tertiary structure. Immunoglobulin: y-shaped; recognizes antigens, viruses & bacteria & removes them. Amino acids are attached in a linear array to create the 1o structure (i. e. a polypeptide) ctions polypeptide) Amino end = n-terminus = positive charge. Carboxyl end = c-terminus = negative charge. 20 unique amino acids are incorporated into a newly synthesized polypeptide.
