BIOLOGY 4X03 Lecture Notes - Lecture 2: Fick'S Laws Of Diffusion, Blood Pressure, Cardiac Output
20 Sep 2016
School
Department
Course
Professor
Document Summary
If envt oxygen is not a problem, the oxygen cascade would be. Ventilation -> pulmonary o2 diffusion -> circulatory o2 delivery -> tissue o2 diffusion -> cellular resp and atp supply. The max metabolic rate of animals is going down, so limitation in increasing temp to get oxygen to tissues. Co x (cao2 cvo2: arterial venous difference, normally through decrease in vo2, so the tissues extract more oxygen. In mammals in exercise, more oxygen demand by muscle tissue so vo2 goes down: oxygen in arterial blood: not a lot that will increase content. Hb concentration bc oxygen bound to hb increases the ability of blood to hold oxygen: co = hr * sv. Ways to increase cardiac output? o o. Pacemaker, modulated by decrease psns input and increase sns input. Dec esv through inc contractility and adrenergic innervation o. Inc venous return: this is what is available to increase oxygen delivery in inc temp.
