HTHSCI 1DT3 Lecture Notes - Lecture 11: Salbutamol, Budesonide, Chronic Obstructive Pulmonary Disease
13 Aug 2020
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Introduction: distinct therapeutic advantage using inhaled therapy, target drug directly to the lung, unlike oral route, able to use smaller drug dose (100 times lower dose than oral route, rapid onset of action (no first pass metabolism) Incidence of side effects is lesser due to lower dose used (oral steroid osteoporosis) Inhalation of essential oils, pine and eucalyptus to alleviate chest symptoms: cigarettes are used to deliver tobacco mixtures via inhalation. Exam: there are many different types of inhaler devices and drugs combination can cause confusion, devices: pmdi, spacers, dpi, nebulisers. Inhaled drugs: 2-agonists, corticosteroids, anti-muscarinic and cromoglycate (mast cells stabilisers: professionals could be uncertain about inhaler use. Most health care workers (junior doctors and respiratory nurses) are uncertain about the correct use of inhalers when compared with respiratory physiotherapists (pt) Pt received more instruction in training (77%) as compared to doctors (43%)
