HTHSCI 1G03 Lecture Notes - Lecture 18: Ventromedial Prefrontal Cortex, Electrodermal Activity, Limbic System

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Limbic system and neocortex: limbic system has bidirectional anatomical connecting with the neocortex, the neuroanatomical arrangement suggests 2 possible effects, limbic system modulates cortical activity, cortex modulates limbic activity, functionality, feelings can affect cognition, and vice versa. Why do controls shift their response, but patients do not: controls must feel that decks a + b are bad, without being aware. Some feeling when reached to where penalty was experienced: controls, gsr before turning up a card in a + b, anticipatory, vm, no anticipatory gsr before turning over card. Amygdala vs vmf: without amygdala, without vmf, doesn"t form association between stimulus and affect, associations may form, do not utilize associations between stimulus and affect in selecting amongst options (making decision) Somatic marker hypothesis: affective memories play role in decision making, affective memories are attached to bodily sensations like gut feelings, gut feelings (somatic markers of affective memories) alert to negative choices.

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