HTHSCI 1H06 Lecture Notes - Lecture 3: Desmoglein, Myasthenia Gravis, Anaphylaxis
15 Feb 2017
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Immune response from start to finish influenza: a sample immune response. Influenza infection: rna virus that infects the respiratory tract. Expulsive reflexes (need to cough: generalized aches, fever. Antigen presentation: immune responses proceed in a stepwise fashion to protect the host. Intrinsic barriers attempt to prevent pathogens from even entering the body, thereby preventing infection. If the intrinsic barriers fail, the immediate innate immune system (consisting of phagocytes resident in the tissue, complement proteins, and the ability to produce inflammatory mediators) is waiting to respond immediately and kill the invader. This causes proliferation and differentiation of the mature na ve t cells into effector t cells. How to turn on a tcell or bcell: activated t cells then activate b cells through signal 1 (tcr-mhc binding, but this time activating the mhc-expressing cell (the b cell) and signal 2 (costimulation)
