HTHSCI 1H06 Lecture 26: 26- Thyroid and Parathyroid

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Below thyroid cartilage and latera, in front of trachea. Makes colloid, thyroid hormone, and release into bloodstream. Parafollicular cell secretes calcitonin to help with calcium homeostasis. Mostly from subclavian and internal carotid artery, gives rise to superior thyroid artery. Drains into jugular vein from superior thyroid vein. Laryngeal nerve sends motor instruction to vocal chords. All of these structures are at risk during thyroid surgery. Increases bmr (utilizes fuel, consume o2, generate heat) Allows neurons to reset resting potential really quickly. Stimulates breakdown of glycogen (glycogenolysis) and fats (lipolysis for atp production. Stimulates hepatic excretion of cholesterol (ldl), converts cholesterol to bile. Makes heartbeat faster and stronger, relaxes lungs for better ventilation. Helps give blood to tissues for metabolic function. Permissive with most aspects of growth (nervous and skeletal systems) Most important in-utero, to get nervous system to grow and also skeletal system. Amino acid tyrosine + benzene ring (makes t3 lipophilic) Receptors inside cell, affects dna transcription and translation.

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