HTHSCI 1LL3 Lecture Notes - Lecture 13: Histone Acetyltransferase, Gene Expression, Repressor

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Most cells contain the same genes but only certain genes are transcribed in the cells tissues. Different gene expressions at different life stages. Gene expression is a very complex process in eukaryotes (several ways to regulate expression) Every cell has the same dna in the nucleus (different genes are activated depending on the location); adapts to changes in their environment. Translation can start before transcription is finished since there is no nucleus (occur together in the cytosol) Genes in an operon are transcribed into a polycistronic mrna with a start and stop codon for each structural gene (a structural gene codes for a protein) Rna polymerase binds to the promoter upstream of coding regions and this promoter controls transcription of all the genes. Gene regulation in prokaryotes is regulated primarily at the level of transcription (simpler than eukaryotic expression) Repressors are regulatory proteins that prevent the polymerase from binding and initiating transcription negative.

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