HTHSCI 1LL3 Lecture Notes - Lecture 4: Alpha Helix, Alpha And Beta Carbon, Amine

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The building blocks of proteins: proteins are big long strings of amino acids. All the proteins in the body are made from the 20 amino acids coded for by our dna: there are others, but they aren"t used for dna instruction, agct are used to specify for certain amino acids. The unique sequence of amino acids in each protein (the primary sequence) predicts its conformation: primary sequence sets the plan for the protein. General structure: hemoglobin ahs quaternary structure (more than one subunit) All of the 20 amino acids have a common structure: backbone is the same, side chain is different, 2 alpha chains, 2 beta chains with a (cid:498)heme(cid:499) group to hold oxygen. The alpha (cid:523) (cid:524) carbon is substituted with an amino group, a carboxylic acid. At physiological p( amino acids exist as (cid:498)zwitterions(cid:499), where both the amino. At this ph the molecule is neutral, this is not the case when the ph changes.

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