HTHSCI 1LL3 Lecture Notes - Lecture 12: Color Blindness, The Sequence, Myelofibrosis

• School: McMaster University
• Department: Health Sciences
• Course: HTHSCI 1LL3
• Professor: Dr. Terry McCurdy

Document Summary

An example is the pattern of inheritance for colour blindness, an x-linked trait. Both characteristics and diseases can be transmitted. Since males have only one copy of the x gene, they are more likely to be colourblind (1 in 12 vs. 1 in 250) Females have to inherit 2 copies of the defective gene. A slight change between people"s dna not really a (cid:498)mutation(cid:499), just variation as in snps. Different individuals may have a slightly different sequence of nucleotides, Mutations are introduced when dna replicates and sometimes this is not repaired, leaving a different nucleotide than the original, this is not always a bad thing. Changes to the ways the genes are expressed. A layer ontop of the dna that controls when, where, and how much of the. The prefix (cid:498)epi(cid:499) means (cid:498)on top of(cid:499); epigenetics studies changes to the expression of genes, without any change in the underlying dna sequence.