KINESIOL 2G03 Lecture Notes - Lecture 7: Corticotropin-Releasing Hormone, Adrenal Medulla, Autoimmunity

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Tb is a bacterial, highly infectious disease, airborne, rate is high in clustered impoverished areas. Used to place patients in a sanatorium (jail like) We used to be stressed due to fear of being hunted. Now our stressors (social evaluation) still activate same stress response. Physical and psychological stress activate the fight or flight response: decreased saliva, chills and sweating, heart beat increases, decreased digestion, pupils dilate, etc. Locus coeruleus becomes active during psychological threats, it then releases norepinephrine to activate hypothalamus: activates sam and hpa. Sam (sympathetic adrenal medulla: rapid stress response that triggers fight or flight, hypothalamus innervates the adrenal medulla through sympathetic innervation, epinephrine is released into the blood stream to bind to receptors, fast and peaks right away. Cytokines are important signalling molecules in the immune system. White blood cells lymph cells t-cells th1 and 2 cells (cytokines: t-helper. Epinephrine and cortisol interact with lymph nodes to alter th1 and 2 balance.

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