MEDRADSC 1B03 Lecture Notes - Lecture 3: Starling Equation, Extracellular Fluid, Frostbite

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First: nonspecific, mechanical barrier (skin mucous, tears, saliva) Second: nonspecific, inflammation and phagocytosis (neutrophils and macrophages) Third: specific, immune response (reacts specifically to the type of infection or processes and differently for each) All are not open: only when needed, precapillary sphincters restrict flow (frostbite) Net hydrostatic pressure: pressure that determines if the fluid, electrolytes, and nutrients will move out of the capillary and into the interstitial fluid. Based on the difference between the capillary hydrostatic pressure and the interstitial hydrostatic pressure and fluid will tend to move to the lower pressure on the venous side. Diffusion of the electrolytes, glucose, oxygen, and nutrients cross the membrane based on the concentration levels in the blood. Excess fluid and any proteins are picked up from the interstitial area by the lymphatic system. (swelling and redness) Body"s response to tissue injury and is non specific.

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