MEDRADSC 2I03 Lecture 16: Inflammatory Comparing

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Loss of joint cartilage and reactive new bone formation. Joint space narrowed, complete fibrous and bony fusion. Inflammation of synovial membrane erosion of articular cartilage underlying bony cortex and ligaments. Affected small joints of hands and feet, very serious when it affects the spine (c1/c2) Steroids and anti- inflammatory drugs, finger implants (synthetic joints), medical botox. Acute hematogenous osteomyelitis: involves bone with rich red marrow. Hematogenous spread, nearby infections, trauma (open or closed) Diabetics (or others with vascular insufficiency): abscess of the bone or decubitus ulcer soft tissue infection cellulitis osteomyelitis in adjacent bone (spreads to the medullary cavity to surface) Fusiform periarticular soft tissue swelling; spindle-like (large on middle and taper) Periarticular osteoporosis- next to joint and then entire bone. Periarticular sclerotic edges (densities easy to see compared to ra) Dislocation of one thumb (left), subluxation of the other (right) Mcp joints not as far along as the previous.

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