MEDRADSC 2S03 Lecture Notes - Lecture 1: Xeroderma Pigmentosum, Tanning Bed, Ionizing Radiation
24 Jun 2016
School
Department
Course
Professor
Document Summary
Incidence/prevalence: most common cancer, risk: 50% of developing skin cancer if live to 65 years, bcc > scc > mm. Age: any age: most cancers in >50 years, mm affecting more young adults. Gender: mm: male slightly > female, bcc, scc m:f = 3:1, bcc, scc legs: f>m. Race: caucasians (fair skin, hair) (in particular blue eyes red hair, african american scc>bcc. Geographic location: near equator (increased uv, high altitudes. Tanning (uva, uvb: use of tanning beds o. Environmental: occupations with high sun exposure, burns or chronic heat exposure (scc) o. Fair complexion: xeroderma pigmentosum; basal cell nevus syndrome, giant hairy nevi o. Fam-m syndrome (family history of melanoma, ++ moles, distinct histological characteristics: previous skin cancer. Skin is formed by connective tissue, covered by a layer of epithelial tissue. Dermis: deeper layer, connective tissue contains blood and lymphatic vessels, nerves and nerve endings, sweat glands, hair follicles.
