MEDRADSC 2T03 Lecture Notes - Lecture 29: Nevoid Basal-Cell Carcinoma Syndrome, Brain Tumor, Medulloblastoma
25 Jun 2016
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Incidence: relatively rare <2% of all brain tumours, less common in adults, 20%-40% of brain tumours in children under 15 years of age. Frequently between 4-8 years of age: most common pnet (primitive neuroectodermal tumour) Age: children: usually diagnosed under age 10. About 50% of cases occur younger than age 6. Typically in first 8 years of life: adults: between ages 20-44. Gender: twice as often in m than f. Genetics: nevoid basal cell carcinoma syndrome (nbccs) aka gorlin syndrome. Tumours located in cerebellum/posterior fossa: unusual for tumours to spread outside of brain. Coordinates voluntary movements: balance, posture, coordination, speech. Contains about half of brain"s neurons https://www2. aofoundation. org/wps/portal/surger ymobile?contenturl=/srg/93/01- Can spread to: bone marrow, lymph nodes, liver, bones, lungs. Greatest potential to spread out of all cns tumours. Problems with handwriting and other motor skills. Staged based on level of risk (average or high) Tumour located at very back of brain.
