NURSING 2LA2 Lecture Notes - Lecture 18: Blood Vessel, Exudate, Necrosis
27 Sep 2018
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Document Summary
Inflammation: the reaction of vascularized tissues to injury: characterized by inflammatory mediators, localizes and eliminates foreign particles and paves the way for repair of injured tissue. Inflammatory conditions are named by adding the suffix -it is. The five cardinal signs of inflammation are: redness, swelling, heat, pain, loss of function. In addition to cardinal signs, systemic or constitutional manifestations may occur as chemical mediators produced at the site of inflammation gain entrance to the circulatory system. Acute-phase response: the constellation of systemic manifestations that may occur during acute inflammation. Degree of inflammatory response is impacted by multiple factors like duration of insult, type of foreign agent, degree of injury, and the microenvironment. Early reaction of local tissues and their blood vessels to injury. Occurs before adaptive immunity and helps remove injurious agent and tissue damage. Acute inflammation involves vascular and cellular stages: tissues involved: endothelial cells, wbc, ct cells, and components of ecm.
